Revolutionizing bone regeneration: advanced biomaterials for healing compromised bone defects

In this review, we explore the application of novel biomaterial-based therapies specifically targeted towards craniofacial bone defects. The repair and regeneration critical sized defects in region requires use bioactive materials to stabilize expedite healing process. However, existing clinical approaches face challenges effectively treating complex defects, including issues such as oxidative stress, inflammation, soft tissue loss. Given that a significant portion individuals affected by traumatic area belong aging population, there is an urgent need for innovative biomaterials address declining rate new formation associated with age-related changes skeletal system. This article emphasizes importance semiconductor industry-derived potential solution combat stress bone. Furthermore, discuss various material autologous treatment approaches, well vitro vivo models used investigate therapeutic strategies context repair. By focusing on these aspects, aim shed light advanced overcome limitations current treatments pave way more effective efficient interventions